Changes in global gene expression patterns caused by acute deletion of TERT in spermatogonial stem cells
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https://www.ncbi.nlm.nih.gov/sra/SRP250205
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资源简介：
To understand the catalytic activity-independent functions of TERT in global gene expression, we acutely deleted TERT in spermatogonial stem cells in the testis, and performed RNA-seq. We find significant down-regulation of MYC pathway genes in TERT-deleted SSCs. Overall design: TERT was acutely deleted by tamoxifen-dependent Cre-LoxP system, and RNA-seq libraries were prepared from SSCs purified by FACS.
创建时间：
2024-07-16
