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Crystal Structure of XIAP-BIR3 domain in complex with Smac-mimetic compuond, Smac005

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Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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Crystal Structure of XIAP-BIR3 domain in complex with Smac-mimetic compuond, Smac005 Descriptor: (3S,6S,7S,9aS)-6-{[(2S)-2-aminobutanoyl]amino}-N-(diphenylmethyl)-7-(hydroxymethyl)-5-oxooctahydro-1H-pyrrolo[1,2-a]azepine-3-carboxamide, Baculoviral IAP repeat-containing protein 4, ZINC ION Authors: Mastrangelo, E, Cossu, F, Milani, M. Deposit date: 2008-03-21 Release date: 2008-10-28 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Targeting the X-linked inhibitor of apoptosis protein through 4-substituted azabicyclo[5.3.0]alkane smac mimetics. Structure, activity, and recognition principles. J.Mol.Biol., 384, 2008

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2008-03-21
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