Experimental design.
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https://figshare.com/articles/dataset/_Experimental_design_/671943
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Thirty 2-week old SPF-chickens were randomly distributed into three groups. Animals received the first inoculum (day 0) and 2 weeks later (day 15), birds were challenged with the respective inoculum 2. Six birds from G1 and G2 were consecutively infected 2 weeks later (day 30) with the third inoculum.
Abbreviations: LPAIV = low pathogenic avian influenza virus; HPAIV = highly pathogenic avian influenza virus.
aChickens from G1 were inoculated intranasally with LPAIV A/Anas plathyrhynchos/Spain/1877/2009 (H7N2) (105.5 ELD50). Birds from G2 and G3 received saline solution.
bChickens from G1 and G2 were intranasally challenged with HPAIV A/FPV/Rostock/34 (H7N1) (105.5 ELD50) 15 days after the pre-exposure to H7N2 LPAIV. Birds from G3 received saline solution.
cChickens from G1 and G3 were inoculated intranasally with 104.5 ELD50 of A/Great crested grebe/Basque Country/06.03249/2006 (H5N1) 15 days after the challenge with H7N1 HPAIV.
创建时间:
2013-03-04



