Emergent metastatic heterogeneity of primary tumor cells is restricted by the Ig-transmembrane protein VSIG IV. Emergent metastatic heterogeneity of primary tumor cells is restricted by the Ig-transmembrane protein VSIG IV
收藏NIAID Data Ecosystem2026-03-11 收录
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Our study prompeted us to assign, through spiked single cell RNAseq, metastatic function to transcriptomic cluster of colon cancer cells. Interactions between clones also uncover a restrictive anti metastatic influence that act intrinsically and non-cell automomously. We identify VSIG1 as critical mediator of this influence. Overall design: RNAseq of clone C11 infected with lentivirus for shVSIG1 and PLKO
创建时间：
2020-03-03
