Damaged tissues have increased risk of cancer development through poorly understood mechanisms. For example, in the pancreas, tissue damage collaborates with activating mutations in the Kras oncogene

NIAID Data Ecosystem20

Gcn5-mediated histone acetylation governs nucleosome dynamics in spermiogenesis [ATAC-seq]

精子发生

染色质可及性分析

During mammalian spermatogenesis, male germ cells undergo dramatic reorganization of chromatin, whereby 90-99% of histones are evicted and replaced by protamines. This reorganization prominently feat

NIAID Data Ecosystem20

Tracking chromatin state changes using nanoscale protoproximity labeling (ATAC-Seq)

染色质可及性分析

功能研究

Effect of histone mutation H2A E92K on open reading frames in HEK293T cells Comparative gene expression profiling analysis of ATAC-seq data for HEK293T cells transfected with H2A or H2A(E92K). *reads

NIAID Data Ecosystem20

Pygopus2-Histone interaction is important for de-differentiation and breast cancer progression [ATAC-Seq]

乳腺癌分子机制

染色质可及性分析

Pygopus2 (Pygo2), a co-activator of Wnt/ β-catenin signaling can also bind H3K4me2/3 and participate in chromatin reading and writing. To investigate the functional relevance of histone binding activi

NIAID Data Ecosystem20

Ananas comosus DNase-seq Raw sequence reads. Ananas comosus

资源简介：

相关数据集