HDX-MS of alpha-synuclein oligomers

NIAID Data Ecosystem2026-05-02 收录

蛋白构象分析

神经退行性机制

数据链接：

https://www.omicsdi.org/dataset/pride/PXD038573 数据链接链接失效反馈

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资源简介：

Here we have used HDX-MS to investigate the change in structure/dynamics in synuclein oligomers formed under different conditions.

创建时间：

2024-05-24

Table_3_Resveratrol: Multi-Targets Mechanism on Neurodegenerative Diseases Based on Network Pharmacology.xlsx

网络药理学

神经退行性机制

Resveratrol is a natural polyphenol in lots of foods and traditional Chinese medicines, which has shown promising treatment for neurodegenerative diseases (NDs). However, the molecular mechanisms of i

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Molecular dynamics simulation data for the publication "Auxiliary subunits reshape structural asymmetry and functional plasticity in heterotetrameric GluA1/A2 AMPA receptor core"

AMPA受体动力学模拟

蛋白构象分析

This dataset contains molecular dynamics simulation trajectories and the initial coordinates for the production runs of all simulated structures. Description of the Data and File Structure The data

Zenodo2026-03-15 更新00

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神经退行性机制

蛋白质相互作用组学

Drp1 interactome in neurons derived from HD patient iPS cells

Figshare2019-03-01 更新00

Additional file 4: of Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer’s disease

神经退行性机制

胶质细胞靶向治疗

Table S4. Putative membrane-associated drug targets and regulators of Blue, Magenta, Yellow and Midnightblue microglial transcriptomic modules. (XLSX 12 kb)

Figshare2018-05-22 更新20

Individual χ2 for EOM models, GI.1 crystallographic dimer and Dadimodo model.

蛋白构象分析

结构验证

EOM models are presented with their fraction used to fit the experimental data. χ2 are calculated with Crysol [46]. a, for this model only the program FOXS [47] is used for computing χ2. The RMSD was

Figshare2017-07-27 更新00

HDX-MS of alpha-synuclein oligomers

资源简介：

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