Crystal Structure of HIV-1 Protease Mutant N88D with novel P1'-Ligands GRL-02031
收藏Protein Data Bank Japan2023-09-13 更新2026-03-21 收录
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Crystal Structure of HIV-1 Protease Mutant N88D with novel P1'-Ligands GRL-02031 Descriptor: (3aS,5R,6aR)-hexahydro-2H-cyclopenta[b]furan-5-yl [(1S,2R)-1-benzyl-2-hydroxy-3-([(4-methoxyphenyl)sulfonyl]{[(2R)-5-oxopyrrolidin-2-yl]methyl}amino)propyl]carbamate, CHLORIDE ION, GLYCEROL, ... Authors: Yu, X.X, Wang, Y.F, Chang, Y.C.E, Weber, I.T. Deposit date: 2012-01-09 Release date: 2012-11-21 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Potent antiviral HIV-1 protease inhibitor GRL-02031 adapts to the structures of drug resistant mutants with its P1'-pyrrolidinone ring. J.Med.Chem., 55, 2012
创建时间：
2012-01-09
