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Ribba2018 - Mathematical Model of Tumor Uptake for Immunocytokine-Based Cancer Immunotherapy

NIAID Data Ecosystem2026-03-11 收录

化疗药代动力学

免疫细胞因子浓度预测

数据链接：

https://www.omicsdi.org/dataset/biomodels/MODEL1909050002 数据链接链接失效反馈

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资源简介：

This is a model developed to predict concentrations of cergutuzumab amunaleukin (CEA-IL2v) after various systemic dosing intensities.

应用场景：

创建时间：

2019-11-13

放射性药物分布

化疗药代动力学

Targeted α particle therapy (TAT) is ideal for treating disease while minimizing damage to surrounding nontargeted tissues due to short path length and high linear energy transfer (LET). We developed

NIAID Data Ecosystem40

Table1_Population pharmacokinetic study of pemetrexed in chinese primary advanced non-small cell lung carcinoma patients.xlsx

化疗药代动力学

个体化优化

The purposes of this study were to identify physiological and genetic factors that contributed to variability of pemetrexed (PEM) exposure and to optimize the dosing regimens for Chinese non-small cel

NIAID Data Ecosystem20

Importance of Intracellular pH in Determining the Uptake and Efficacy of the Weakly Basic Chemotherapeutic Drug, Doxorubicin

化疗药代动力学

细胞内pH

Low extracellular pH (pHe), that is characteristic of many tumours, tends to reduce the uptake of weakly basic drugs, such as doxorubicin, thereby conferring a degree of physiological resistance to ch

Figshare2016-01-19 更新10

Data_Sheet_4_Model-Based Simulation of Maintenance Therapy of Childhood Acute Lymphoblastic Leukemia.PDF

白血病研究

化疗药代动力学

Acute lymphoblastic leukemia is the most common malignancy in childhood. Successful treatment requires initial high-intensity chemotherapy, followed by low-intensity oral maintenance therapy with oral

NIAID Data Ecosystem20

Pharmacokinetic profiles before and after chemotherapy.

化疗药代动力学

维生素代谢

The data are presented as mean ± SD.* Moles of oxalic acid excreted per 100 mol of vitamin C administered.** Wilcoxon matched pairs test (GraphPad Prism version 5.01).Pharmacokinetic profiles before a

Figshare2015-12-03 更新10

Ribba2018 - Mathematical Model of Tumor Uptake for Immunocytokine-Based Cancer Immunotherapy

资源简介：

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