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CP003: Modulation of glutamine metabolism by the PI3K-PKB/c-akt-FOXO network regulates autophagy

ChEBI2012-07-21 更新2026-07-21 收录

自噬调控机制

代谢信号通路

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-35703 数据链接链接失效反馈

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资源简介：

CP003: Modulation of glutamine metabolism by the PI3K-PKB/c-akt-FOXO network regulates autophagy

应用场景：

创建时间：

2012-07-21

肥胖症

代谢信号通路

Introduction: Abnormalities in adipose tissue AdipoR1; adaptor protein, phosphotyrosine interaction, PH domain, and leucine zipper containing 1 (APPL1); GTPase Rab5; adiponectin; leptin;

DataCite Commons2020-10-19 更新80

Cytokine Signaling Co-opts the CREB/CRTC Pathway in Obesity

肥胖机制

代谢信号通路

Obesity stimulates the infiltration of adipose tissue by innate immune cells, which in turn promote insulin resistance via the NFkB mediated induction of pro-inflammatory cytokines, which interfere wi

NIAID Data Ecosystem40

HECTD1-mediated ubiquitination and degradation of Rubicon regulates autophagy and osteoarthritis pathogenesis

自噬调控机制

关节炎分子机制

Osteoarthritis (OA) is one of the most common degenerative joint diseases and is associated with autophagy suppression. However, the molecular mechanism of autophagy regulation in the context of OA is

NIAID Data Ecosystem30

Bcl-xL complex with Beclin 1 BH3 domain T108pThr

蛋白质复合物结构解析

自噬调控机制

Bcl-xL complex with Beclin 1 BH3 domain T108pThr Descriptor: BCL-xl protein, Beclin-1 Authors: Lee, E.F, Smith, B.J, Smith, N.A, Yao, S, Fairlie, W.D. Deposit date: 2018-05-07 Release date: 2018-05-23

Protein Data Bank Japan2024-11-06 更新50

Additional file 8 of Comparative transcriptomic and metabolic profiling provides insight into the mechanism by which the autophagy inhibitor 3-MA enhances salt stress sensitivity in wheat seedlings

盐胁迫响应

自噬调控机制

Additional file 8: Table S5. The effect of 3-MA on GO significant enrichment of DEGs in roots of wheat seedings under NaCl stress.

Figshare2021-12-07 更新40