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Functional Dissection of Variant Polycomb Repressive Complex 1 Subunits RYBP and YAF2 during Neural Differentiation of Embryonic Stem Cells [ChIP-Seq]

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NIAID Data Ecosystem2026-05-01 收录
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Chromatin immunoprecipitation sequencing (ChIP-seq) for RING1B, RYBP, YAF2, PRC2 complex (EZH2, MTF2 and JARID2) as well as the histone modifications H2AK119ub, H3K27me3 and H3K27ac in mESCs and the neural differentiated cells. Overall design: Rybp-/- and Yaf2-/- mESC lines were generated by using CRISPR/Cas9 technique. ChIP samples obtained from wild-type, Rybp-/- and Yaf2-/- mESCs and the neural differentiated cells.

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2024-01-09
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