Tumorigenesis in Atm and p53Ser18 deficient animals.
收藏数据链接：
官方服务：
资源简介：
Tumorigenesis in Atm and p53Ser18 deficient animals.
应用场景：
创建时间：
2015-12-02
相关数据集
Gene expression profiling in mouse fibroblast tumors with overexpression of the homeoprotein SIX1
Six1 is a developmental transcriptional regulator frequently overexpressed in human tumors. Recent results also show that SIX1 acts as a repressor of cell senescence, an antiproliferative response wit
NIAID Data Ecosystem110
p53 amyloid formation induced cellular transformation and tumor formation in xenograft model
p53 mutation and its subsequent loss of function along with gain of oncogenic functions is associated with cancer. However, the exact mechanism of how altered p53 acts as an oncogene is not clear yet.
NIAID Data Ecosystem50
OncoSig: a new algorithm for the accurate and systematic de novo prediction of Oncoprotein-centric Signaling networks. OncoSig: a new algorithm for the accurate and systematic de novo prediction of Oncoprotein-centric Signaling networks
We introduce a new algorithm, OncoSig, to address the deficiencies of canonical pathways through the accurate, context-specific prediction of proteins representing both known and novel functional memb
NIAID Data Ecosystem30
Analysis of germinal centers in UNG and AID deficient mice
Analyze kinetics, cell composition and proliferation of germinal center B cells in wt vs Ung-/- vs Aicda-/- vs Ung-/- Aicda-/- mice after immunization with model antigens.
NIAID Data Ecosystem80
Transcriptome changes following loss of Apc in the intestine. Mus musculus
Nearly all colorectal cancers have dysregulated Wnt signalling, predominantly through the mutation of the Apc (Adenomatous Polyposis Coli) gene. Therefore it is of vital importance to elucidate the ke
NIAID Data Ecosystem40
