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X-ray structure of the human alpha-thrombin complex with a tripeptide phosphonate inhibitor.

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Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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X-ray structure of the human alpha-thrombin complex with a tripeptide phosphonate inhibitor. Descriptor: HIRUDIN I, N-[(benzyloxy)carbonyl]-beta-phenyl-D-phenylalanyl-N-{(1S,3E)-1-[dihydroxy(diphenoxy)-lambda~5~-phosphanyl]-4-methoxybut-3-en-1-yl}-L-prolinamide, THROMBIN Authors: Skordalakes, E, Dodson, G.G, Green, D, Deadman, J. Deposit date: 2001-02-01 Release date: 2001-02-26 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Inhibition of Human Alpha-Thrombin by a Phosphonate Tripeptide Proceeds Via a Metastable Pentacoordinated Phosphorus Intermediate J.Mol.Biol., 311, 2001
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2001-02-01
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