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RNA sequencing of MC38 syngeneic tumor tissue treated +/- RXDX-106, +/- anti-PD1 combination study

NIAID Data Ecosystem2026-04-25 收录

肿瘤免疫联合疗法

肿瘤微环境转录组

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP151308 数据链接链接失效反馈

官方服务：

资源简介：

Monitor RNA changes in the MC38 syngeneic tumor microenvironment as a result of RXDX-106 treatment +/- anti-PD1 combination study

应用场景：

创建时间：

2019-07-25

肿瘤免疫联合疗法

胰腺癌热消融机制

Pancreatic cancer (PC) is a devastating disease characterised by late diagnosis, genetic neoplastic heterogeneity, poor T-cell infiltration, a highly immunosuppressive tumour microenvironment, and met

NIAID Data Ecosystem40

Significantly regulated cell populations in the lenalidomide plus cetuximab arm.

肿瘤免疫联合疗法

免疫细胞群体分析

*Cell populations that are unique to the lenalidomide plus cetuximab arm only. Abs, absolute; C1D1, cycle 1 day 1; C2D1, cycle 2 day 1; C3D1, cycle 3 day 1; FC, fold change; NK, natural killer.

NIAID Data Ecosystem20

Supplementary Table from An Immunogenic Model of KRAS-Mutant Lung Cancer Enables Evaluation of Targeted Therapy and Immunotherapy Combinations

KRAS突变治疗

肿瘤免疫联合疗法

Supplementary Table from An Immunogenic Model of KRAS-Mutant Lung Cancer Enables Evaluation of Targeted Therapy and Immunotherapy Combinations

NIAID Data Ecosystem10

Effects of ascites exposure from ovarian cancer on epithelial cancer cell lines

卵巢癌转移机制

肿瘤微环境转录组

Ascites is an abnormal fluid that accumulates in the peritoneal cavity of more than 90% of patients with metastatic ovarian cancer. Despite its common occurance, little is known about its effects on d

NIAID Data Ecosystem30

Transcription landscape of adipose tissue and tumor in response to adipose stromal cell depletion. Transcription landscape of adipose tissue and tumor in response to adipose stromal cell depletion

脂肪基质细胞

肿瘤微环境转录组

Mice grafted with Myc-Cap tumor were treated (3 weeks) with a pro-apoptotic peptide D-CAN targeting adipose stromal cells or PBS (control). Overall design: In the end of treatment, tumor cells and str

NIAID Data Ecosystem20

RNA sequencing of MC38 syngeneic tumor tissue treated +/- RXDX-106, +/- anti-PD1 combination study

资源简介：

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