Number of nonsynonymous and synonymous variants identified in APOA1 by apoA-I percentiles.

aP-values by Fisher's exact test comparing nonsynonymous (NS) and synonymous (S) variants combined and identified exclusively in the low apoA-I or in the high apoA-I group. Values represent the cumulative number of genetic variants identified in the lowest and highest 0–1 percentile, 0–5 percentile and 0–10 percentile, 0–20 percentile and 0–50 percentile of the apoA-I distribution in the Copenhagen City Heart Study.bThe upper and lower 0–50 percentiles combined correspond to the total number of nonsynonymous and synonymous variants identified in the Copenhagen City Heart Study.