SNPs associated with Alzheimer’s disease risk.

Abbreviations: SNPs, single nucleotide polymorphisms; Chr, chromosome; n, number of cases; MAF, minor allele frequency; OR, odds ratio; CI, confidence interval; 0ε4, APOE ε4 allele noncarriers; 1ε4, carriers of 1 APOE ε4 allele; 2ε4, carriers of 2 APOE ε4 alleles.Multiple comparison analysis (overall) was calculated by Pearson chi-square test. Univariate and multivariate analyses were calculated using binary logistic regression assuming a dominant model. Multivariate analyses were adjusted for age, sex and APOE-ε4 status. Analyses testing APOE adjusted for age and gender. Results for APOE are shown for comparative purposes.aSignificant at false discovery rate adjusted PbNot significant after false discovery rate correction.cMinor allele frequency not computed because APOE is tri-allelic.