Metal-Free [2 + 2 + 2] Cycloaddition of Ynamide–Nitriles with Ynamides: A Highly Regio- and Chemoselective Synthesis of δ‑Carboline Derivatives
收藏NIAID Data Ecosystem2026-03-10 收录
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https://figshare.com/articles/dataset/Metal-Free_2_2_2_Cycloaddition_of_Ynamide_Nitriles_with_Ynamides_A_Highly_Regio-_and_Chemoselective_Synthesis_of_Carboline_Derivatives/7243232
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资源简介:
A metal-free
formal [2 + 2 + 2] cycloaddition of functionalized
ynamide–nitriles with ynamides is disclosed which offers highly
efficient access to polysubstituted δ-carboline derivatives
under the mediation of TfOH. This strategy is highly regioselective
and chemoselective and displays mild conditions, high yields, and
efficiency (within 1 min) in addition to substrates scopes (56 examples).
创建时间:
2018-10-23



