Phosphatase MAP4K4 regulates neutrophil development through the apoptosis pathway
收藏NIAID Data Ecosystem2026-05-02 收录
下载链接：
https://www.ncbi.nlm.nih.gov/sra/SRP530787
下载链接
链接失效反馈官方服务：
资源简介：
The role of MAP4K4 in the development of neutrophils remains largely unexplored. We utilized single cell sequencing (scRNA-seq) technology to elucidate the impact of Map4k4 deficiency on neutrophil maturation within mouse bone marrow. Through the application of scRNA-seq, we characterized the transcriptional changes across various stages of neutrophil development in both Map4k4-deficient (Map4k4-cKO) and control mice. Overall design: Control or Map4k4-cKO mice c-Kit+ BM HSPCs mixed with BM cells at a 2:3 ratio to create a c-Kit/BM population artificially and analyzed using scRNAseq
创建时间：
2025-02-13
