Transcriptional and post-transcriptional regulation of VEGF by the unfolded protein response

ChEBI2011-05-13 更新2026-07-21 收录

未折叠蛋白反应研究

VEGF信号通路

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-21979 数据链接链接失效反馈

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Transcriptional and post-transcriptional regulation of VEGF by the unfolded protein response

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2011-05-13

血管内皮生长因子165通过DLL4/Nnotch4/smad7途径抑制基质细胞的促纤维化分化。

子宫内膜纤维化

VEGF信号通路

子宫内膜细胞分泌的许多因子参与了子宫内膜重塑和再生过程中稳态的恢复。血管内皮生长因子A（VEGFA）的主要亚型是VEGF165，是在月经后子宫内膜修复和增生早期时上皮和基质细胞中显著上调的因子之一。众所周知，VEGFA对血管生成的快速爆发至关重要，并通过参与上皮和基质之间的串扰来调节子宫内膜的再上皮化。子宫内膜VEGFA的上调通常是评估子宫内膜损伤治疗效果的重要指标。转化生长因子β（TGFβ）信号

干细胞与再生医学数据中心2023-07-14 更新220

Pleiotrophic roles of VEGF during neonatal thymic development

胸腺发育生物学

VEGF信号通路

In this report, we show that VEGF-blockade in neonates induces rapid changes in all three stromal compartments of the thymus, and that these changes recapitulate the maturation of these cell types see

NIAID Data Ecosystem80

Supplementary Material for: Coxsackievirus B Tailors the Unfolded Protein Response to Favour Viral Amplification in Pancreatic β Cells

病毒-宿主相互作用

未折叠蛋白反应研究

Type 1 diabetes (T1D) is an autoimmune disease characterized by islet inflammation and progressive pancreatic β cell destruction. The disease is triggered by a combination of genetic and environmental

NIAID Data Ecosystem60

Sequencing of Argonaute-bound miRNA/mRNA hybrids reveals regulation of the unfolded protein response by microRNA-320a. Sequencing of Argonaute-bound miRNA/mRNA hybrids reveals regulation of the unfolded protein response by microRNA-320a

非编码RNA调控

未折叠蛋白反应研究

MicroRNAs (miRNA) are short non-coding RNAs widely implicated in development, gene regulation, and disease progression. Most miRNAs utilize the RNase III enzymes Drosha and Dicer for biogenesis in ani

NIAID Data Ecosystem80

Response of murine lymphatic endothelial cells to stimulation with vascular enothelial growth factor-C (VEGF-C). Mus musculus

淋巴管内皮细胞转录组

VEGF信号通路

The goal of this study is to investigate changes in gene expression profile of lymphatic endothelial cells (LECs) following stimulation with VEGF-C. Primary murine LECs from C57Bl/6 mice were expanded

NIAID Data Ecosystem70

Transcriptional and post-transcriptional regulation of VEGF by the unfolded protein response

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