Purpose: The goal of this study is to identify transcriptome-wide changes that occur in a human prostate cell line with knockdown of MAP3K7(TAK1) and CHD1, in the presence and absence of androgens. We

NIAID Data Ecosystem50

Naturally-occurring canine invasive urothelial carcinoma harbors luminal and basal transcriptional subtypes found in human muscle invasive bladder cancer . Naturally-occurring canine invasive urothelial carcinoma harbors luminal and basal transcriptional subtypes found in human muscle invasive bladder cancer

膀胱癌分子亚型

跨物种肿瘤转录组学

RNA-seq was used to identify basal and luminal subtypes in canine bladder cancer. In addition to larger gene-sets, a smaller panel of genes was developed to stratify canine samples into either basal o

NIAID Data Ecosystem20

Urothelial-to-Neural Lineage Plasticity Drives Progression to Small Cell Bladder Cancer

癌症谱系可塑性

膀胱癌分子亚型

Small cell carcinoma (SCC) of the bladder displays a high propensity for distant metastasis and is associated with short survival. We report a comprehensive molecular analysis of 34 cases of SCC and 8

NIAID Data Ecosystem70

TMPRSS2-ERG fusion prostate cancer is a molecularly distinct estrogen-sensitive subclass of aggressive prostate cancer

膀胱癌分子亚型

基因融合表达

Common epithelial cancers are believed to become more aggressive through the accumulation of multiple independent molecular events that lead to the deregulation of cell signaling. However, the discove

NIAID Data Ecosystem30

Additional file 3 of Subtype-associated epigenomic landscape and 3D genome structure in bladder cancer

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