Mass spectrometry analysis of post-translational modifications of K/C-III-expressing HEK293T cells treated by A485 for 6 and 12 hours
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To determine whether CBP/P300 HAT activity is essential for leukemia cell maintenance, we utilized the selective acetyltransferase inhibitor A485. Mass spectrometry analysis of post-translational modifications showed that A485 treatment of K/C-III-expressing HEK293T cells for 6 and 12 hours significantly reduced multiple histone acetylation marks.
创建时间：
2025-08-08
