4 Single cell RNA-seq samples exposed to nano plastic particles

Nanoscale Material Size Shapes Distinct Immune Transcriptional States Under Physiological Flow In this study, we exposed human peripheral blood samples to carboxylated polystyrene nanoparticles of different particle sizes and performed single-cell RNA sequencing to examine their effects on gene expression profiles. We leveraged scRNA-seq to investigate the transcriptional consequences of PSNPs of varying sizes: 40 nm (Sample 1), 200 nm (Sample 2), and a combined 40+200 nm mixture (Sample 3) - on human peripheral blood immune cells compared against control sample from the same person, without exposure to PSNPs (Sample 4).