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Gene expression profiling of HtrA2/Omi S400D mice liver

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE223095
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To study the role of HtrA2/Omi S400 phosphorylation, we generated knock in mice with HtrA2/Omi S400D mutation which mimics constitutive S400 phosphorylation of HtrA2/Omi. Wildtype C57BL6/N mice, as well as mice with heterozygous or homozygous HtrA2/Omi S400D mutation were euthanized at the age of 2 months and liver was used for RNA sequencing.
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2023-01-29
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