Genome wide differential gene expression analysis of MYCN-amplified neuroblastoma cells after lncNB1 knockdown with siRNAs
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE113998
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We identified that knocking lncNB1 reduces N-Myc protein stability, therefore, we performed affymetrix micoarray studies to investigate whether it was a direct or indirect effect. lncNB1 stabilizes N-Myc protein expression through activating DEPDC1B gene transcription. We performed Affymetrix gene_array and Clariom_S_array in BE(2)-C cells after transfection with Control siRNA, lncNB1 siRNA-1 or lncNB1 siRNA-2 for 40 hours.
创建时间:
2019-11-12



