CBX4 role in U2OS/MTX300
收藏NIAID Data Ecosystem2026-03-11 收录
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资源简介：
In our study, we found that CBX4 was critical to osteosarcoma metastasis.CBX4, also known as polycomb 2 (Pc2), belongs to the CBX protein family, including CBX2, 4, 6, 7, and 8, which has been shown to participate in the polycomb repressive complex 1 (PRC1) and characterized as a transcriptional repressor. To identify the downstream target genes of CBX4 in osteosarcoma, we conducted the RNA-seq analysis of CBX4 overexpression or knockdown in osteosarcoma cell line U2OS/MTX300. U2OS/MTX300 cells overexpressing CBX4 are compared to Vector, and shCBX4 are compared to shControl
创建时间：
2020-03-09
