Pull-down experiments were performed as described in Materials and Methods. The beads were then analysed for bound proteins by mass spectrometry as detailed in the materials and methods. All DUBs iden

NIAID Data Ecosystem40

Structure of the second OTU domain of LotA

蛋白质结构解析

去泛素化酶

Structure of the second OTU domain of LotA

NIAID Data Ecosystem30

The UBA-UIM Domains of the USP25 Regulate the Enzyme Ubiquitination State and Modulate Substrate Recognition

去泛素化酶

蛋白质翻译后修饰

USP25m is the muscle isoform of the deubiquitinating (DUB) enzyme USP25. Similarly to most DUBs, data on USP25 regulation and substrate recognition is scarce. In silico analysis predicted three ubiqui

NIAID Data Ecosystem80

Table1_Emerging Role of Ubiquitin-Specific Protease 19 in Oncogenesis and Cancer Development.XLSX

肿瘤分子机制

去泛素化酶

Ubiquitination and ubiquitin-like post-translational modifications control the activity and stability of different tumor suppressors and oncoproteins. Hence, regulation of this enzymatic cascade offer

NIAID Data Ecosystem40

Rpn11 homolog from Caldiarchaeum Subterraneum, truncated

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