Irak4-inhibitor co-structure
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Irak4-inhibitor co-structure Descriptor: (1R,2S,3R,5R)-3-({5-(1,3-benzothiazol-2-yl)-6-chloro-2-[(3-methoxypropyl)amino]pyrimidin-4-yl}amino)-5-(hydroxymethyl)cyclopentane-1,2-diol, Interleukin-1 receptor-associated kinase 4 Authors: Fischmann, T.O. Deposit date: 2015-01-21 Release date: 2015-05-13 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.73 Å) Cite: Discovery and hit-to-lead optimization of 2,6-diaminopyrimidine inhibitors of interleukin-1 receptor-associated kinase 4. Bioorg.Med.Chem.Lett., 25, 2015
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2015-01-21
