Gut microbiota analysis in poorly controlled diabetes patients with latent TB infection (LTBI) and nonLTBI [16S rRNA]

In previous study, patients with Diabetes Mellitus (DM) have high risk of active TB and LTBI. Here we report and compare 16S rRNA data of DM-LTBI and DM-nonLTBI in gut microbiota to identify differential candidates between the two groups. The results showed the differential genera have potential to predict the LTBI status in patients. Overall design: Microbial DNA from fecal samples including two groups, DM with LTBI (n=43) and non-LTBI (n=87), were amplified by PCR using V3-V4 primers of bacteria.