Cu(II)-Mediated Cross-Dehydrogenative Coupling of Indolines with Sulfonamides, Carboxamides, and Amines
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https://figshare.com/articles/dataset/Cu_II_-Mediated_Cross-Dehydrogenative_Coupling_of_Indolines_with_Sulfonamides_Carboxamides_and_Amines/9920180
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资源简介：
A facile and efficient
Cu-mediated protocol for the cross-dehydrogenative
coupling of indoline with sulfonamides, carboxamides, and anilines
is reported. The reaction takes place through Cu-mediated C7–H
activation via a 6-membered metallacycle to afford the amide and amine
derivatives in good yields with a wide range of functional group tolerance.
The importance of the protocol has been demonstrated by synthesizing
the antiproliferative agent, ER-67836.
创建时间：
2019-09-12
