High-throughput in vitro DROSHA processing on human pri-miRNA variants
收藏NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP237800
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资源简介：
The in vitro high-throughput human pri-miRNA processing assays were conducted to check whether mismatches and wobble base pairs in the upper stem of pri-miRNAs affects the DROSHA cleavage. Overall design: 151,248 variants generated from three human pri-miRNAs (pri-mir-106a, pri-mir-342 and pri-mir-514a-1) were processed by mutant DROSHA. The original substrates and cleaved products were cloned and sequenced.
创建时间：
2020-05-08
