RNA-seq of murine MA9 Gata2 f/f and Gata2 -/- (Gata2 KO) leukemias with Nutlin

NIAID Data Ecosystem2026-05-02 收录

白血病转录组

Gata2基因功能

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE264720 数据链接链接失效反馈

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资源简介：

Transcriptional effects of Nutlin treatment in murine MA9 leukemia after loss of Gata2. RNA-seq of murine MA9 Gata2 f/f and Gata2 KO leukemias with Nutlin. Three independent samples for each condition.

创建时间：

2025-04-30

Next generation sequencing quantitatively analyzes transcriptomes of primary CLL cells tranfected with non-specific control (NSC) or ZAP-70 siRNA (+anti-IgM dataset). Next generation sequencing quantitatively analyzes transcriptomes of primary CLL cells tranfected with non-specific control (NSC) or ZAP-70 siRNA (+anti-IgM dataset)

白血病转录组

RNA干扰功能验证

RNA seq profiles of primary CLL cells transfected with non-specific control (NSC) or ZAP-70 siRNA ± anti-IgM. This submission is +anti-IgM. Overall design: mRNA profiles of primary CLL cells tranfecte

NIAID Data Ecosystem30

RNA-seq of MV-4-11 or THP-1 cells treated with LSD1 inhibitor INCB059872

白血病转录组

表观遗传靶向治疗

INCB059872 is a selective irreversible inhibitor of Lysine-Specific Demethylase 1 (LSD1) that is in phase 1 clinical trials in hematopoietic malignancies. LSD1 inhibition can induce differentiation of

NIAID Data Ecosystem30

Human Chronic Lymphocytic Leukaemia cells: Untreated vs mithramycin-treated. Human Chronic Lymphocytic Leukaemia cells: Untreated vs mithramycin-treated

白血病转录组

转录因子调控

Transcriptional profiling of primary human malignant B cells from patients with chronic lymphocytic leukaemia (CLL), comparing untreated CLL cells with CLL cells that have been treated 24h with 200nM

NIAID Data Ecosystem30

Mitochondrial Fission 1 (FIS1) knockdown effect on the transcriptome of leukemia cell line MOLM-13 cells

白血病转录组

线粒体分裂基因功能

To explore the function of Mitochondrial Fission 1 (FIS1) in acute myeloid leukemia (AML), we used shRNA to knock down the expression of FIS1 in leukemia cell line MOLM-13 cells and performed RNA-seq

NIAID Data Ecosystem30

Expression data from five human leukemia cell lines treated with DMSO or tanshinone IIA

白血病转录组

药物机制研究

Tanshinone IIA (Tan IIA) is a diterpene quinone extracted from the root of Salvia miltiorrhiza, a Chinese traditional herb. Although previous studies have reported the anti-tumor effects of Tan IIA on

NIAID Data Ecosystem30

RNA-seq of murine MA9 Gata2 f/f and Gata2 -/- (Gata2 KO) leukemias with Nutlin

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