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Gene expression profile of thymus transplantation based spontaneous murine T cell acute lymphoblastic leukemia (T-ALL) model

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https://www.ncbi.nlm.nih.gov/sra/SRP220745
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资源简介:
We adapted a spontaneously-arising, genetically-heterogeneous, thymic transplantation-based murine model of T-ALL, recapitulating key histopathological and genetic features of the human disease, to the preclinical testing of targeted and immune-directed therapies. Overall design: Wild-type thymus-derived T-ALL samples, Notch3 knockout thymus-derived T-ALL samples, and controls were subjected to RNA sequencing
创建时间:
2019-10-09
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