PARN is essential to GSIS in beta cell

NIAID Data Ecosystem2026-05-02 收录

细胞功能研究

胰岛素分泌调节

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE248389 数据链接链接失效反馈

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To investigated the function of PARN in beta cells, we generated the specific deletion of Parn in beta cells. To compare the gene expression between Ctrl and cKO

创建时间：

2024-11-20

Selected compounds which alter insulin secretion in acute (hours) and chronic (days) exposure scenario's.

胰岛素分泌调节

药物筛选与作用机制

Reported effects on basal (BIS) and glucose stimulated (GSIS) insulin secretion, and the primary targets via which the compounds exert their effects are given, together with the expected control funct

Figshare2015-12-02 更新60

Table7_PanCircBase: An online resource for the exploration of circular RNAs in pancreatic islets.XLSX

胰腺胰岛

细胞功能研究

Circular RNAs (circRNAs) are a novel class of covalently closed RNA molecules that recently emerged as a critical regulator of gene expression in development and diseases. Recent research has highligh

NIAID Data Ecosystem20

Transcription profiling of human umbilical vein endothelial cells (HUVECs) transduced with pMLV-MCS or pMLV-THAP1 retroviral expression vectors

基因表达谱分析

细胞功能研究

Transcription profiling of human umbilical vein endothelial cells (HUVECs) transduced with pMLV-MCS or pMLV-THAP1 retroviral expression vectors

ChEBI2006-09-11 更新10

The Role of Natural Killer (NK) Cells and NK Cell Receptor Polymorphisms in the Assessment of HIV-1 Neutralization

HIV-1免疫反应机制

细胞功能研究

The importance of innate immune cells in HIV-1 pathogenesis and protection has been highlighted by the role of natural killer (NK) cells in the containment of viral replication. Use of peripheral bloo

NIAID Data Ecosystem50

Supplemental Materials for Mackiewicz et al., 2025

细胞功能研究

蛋白质分泌

Among 959 somatic cells in C. elegans, there is the excretory gland cell, whose function remains unknown. The authors demonstrate that a specific family of secreted proteins, NSPCs, is expressed exclu

NIAID Data Ecosystem10

PARN is essential to GSIS in beta cell

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