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Expression profiling of secondary wild type (WT) and Ezh2-null murine MLL-AF9 AML

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NIAID Data Ecosystem2026-03-10 收录
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We evaluated gene expression changes in secondary recipient murine leukemia caused by retroviral overexpression of MLL-AF9. We compared wild-type (WT) leukemia cells with mutant leukemia cells after cre-mediated inactivation of a homozygous conditional allele for Ezh2, a component of the Polycomb Repressive Complex2. For WT cells, 4 biological replicates were hybridized. For Ezh2-null cells, 5 biological replicates were hybridized.

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2019-02-11
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