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Cystic Fibrosis Pigs Develop Lung Disease and Exhibit Defective Bacterial Eradication at Birth

ChEBI2010-09-17 更新2026-07-21 收录

囊性纤维化动物模型

肺部先天免疫缺陷

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-21071 数据链接链接失效反馈

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资源简介：

Cystic Fibrosis Pigs Develop Lung Disease and Exhibit Defective Bacterial Eradication at Birth

应用场景：

创建时间：

2010-09-17

囊性纤维化动物模型

无义突变治疗验证

Nonsense mutations that lead to the insertion of a premature termination codon (PTC) in the cystic fibrosis transmembrane conductance regulator (CFTR) transcript affect 11% of patients with cystic fib

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Characterization of Defects in Ion Transport and Tissue Development in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)-Knockout Rats

囊性纤维化动物模型

CFTR药物研究

Animal models for cystic fibrosis (CF) have contributed significantly to our understanding of disease pathogenesis. Here we describe development and characterization of the first cystic fibrosis rat,

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Dataset for: Cellular distribution and function of ion channels involved in transport processes in rat tracheal epithelium

囊性纤维化动物模型

离子通道电生理学

Transport of water and electrolytes in airway epithelia involves chloride-selective ion channels, which are controlled either by cytosolic Ca2+ or by cAMP. The contributions of the two pathways to chl

Figshare2017-07-17 更新30

Table_1_Production of CFTR-ΔF508 Rabbits.DOCX

囊性纤维化动物模型

CRISPRi基因编辑

Cystic Fibrosis (CF) is a lethal autosomal recessive disease caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR). The most common mutation is the de

NIAID Data Ecosystem50

Dataset for: Cellular distribution and function of ion channels involved in transport processes in rat tracheal epithelium

气道离子转运机制

囊性纤维化动物模型

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