Constitutive activation of the WNT signaling effector CTNNB1 (β-catenin) in the Sertoli cells of the Ctnnb1tm1Mmt/+;Amhr2tm3(cre)Bhr/+ mouse model results in progressive germ cell loss and sterility.
High-throughput RNA, sRNA and degradome sequencing were conducted to identify a large number of mRNA, miRNAs and their targets in G. biloba ovules at two different developmental stage, which provided
Proper regulation of spermatogonial stem cells (SSCs) is crucial for sustaining steady-state spermatogenesis. Previous work has identified several paracrine factors involved in this regulation, in par
Long-term maintenance of spermatogenesis in mammals is supported by GDNF, an essential growth factor required for spermatogonial stem cell (SSC) self-renewal. Exploiting a transgenic GDNF overexpressi
File 1 of RNA-seq raw data of N48-2 biological replicate 1 spikelets at mononuclear stage. Paired-end sequencing strategy was applied on the Illumina HiSeq 4000 sequencing platform.