Crystal structure of MMP-13 in complex with SC-78080

Crystal structure of MMP-13 in complex with SC-78080 Descriptor: 1-(2-methoxyethyl)-N-oxo-4-({4-[4-(trifluoromethoxy)phenoxy]phenyl}sulfonyl)piperidine-4-carboxamide, CALCIUM ION, Collagenase 3, ... Authors: Kiefer, J.R, Williams, J.M, Becker, D.P. Deposit date: 2009-11-19 Release date: 2010-10-06 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Orally-active MMP-1 sparing alpha-tetrahydropyranyl and alpha-piperidinyl sulfone matrix metalloproteinase (MMP) inhibitors with efficacy in cancer, arthritis, and cardiovascular disease J.Med.Chem., 53, 2010