Mechanism and Catalytic Site Atlas

M-CSA is a database of enzyme reaction mechanisms. It provides annotation on the protein, catalytic residues, cofactors, and the reaction mechanisms of hundreds of enzymes. There are two kinds of entries in M-CSA. 'Detailed mechanism' entries are more complete and show the individual chemical steps of the mechanism as schemes with electron flow arrows. 'Catalytic Site' entries annotate the catalytic residues necessary for the reaction, but do not show the mechanism. The M-CSA (Mechanism and Catalytic Site Atlas) represents a unified resource that combines the data in both MACiE and the CSA

M-CSA 是一个酶反应机制的数据库。该数据库对数百种酶的蛋白质、催化残基、辅因子以及反应机制提供了详细的注释。M-CSA 中包含两种类型的条目。'详细机制'类型的条目更为详尽，通过包含电子流动箭头的方案展示了机制中的个别化学步骤。'催化位点'类型的条目则注释了反应所需的催化残基，但并未展示机制。M-CSA（机制与催化位点图谱）代表了将 MACiE 和 CSA 数据结合的统一资源。