Data from: Systematic computational assessment of atrial function impairment due to fibrotic remodeling in electromechanical properties

This dataset supports our study “Systematic computational assessment of
atrial function impairment due to fibrotic remodeling in electromechanical
properties,” which explores the impact of electromechanical remodeling in
the fibrotic left atrium. It contains deidentified, patient-specific left
atrial geometries; complete parameter sets for baseline and fibrotic
combinations; scripts used to perform the simulations; and the resulting
output files. Each geometry includes fibrosis patterns, fiber
orientations, region tags, and pacing sites. Parameter files specify
alterations in nine fibrosis-associated properties—conduction velocities,
ion channel conductances, active tension scaling, myofilament kinetics,
and tissue stiffness—across one-factor-at-a-time and fractional factorial
sensitivity analysis setups. Simulation and preprocessing scripts are
provided for reproducibility and can be executed using the Carpentry
software framework (Numericor). Output data, provided in CSV format,
include left atrial pressure–volume (PV) loop recordings and hemodynamic
variables from the coupled 3D electromechanical–0D circulatory model for
all simulated conditions. These data quantify atrial work and contractile
performance under varied remodeling scenarios. The dataset is structured
to enable replication of the published results and to support further
investigations into the biophysical determinants of atrial dysfunction and
stroke risk.