A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span

ChEBI2006-03-07 更新2026-07-21 收录

寿命调控基因

线虫衰老机制

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A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span

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2006-03-07

The complete cell atlas of an aging multicellular organism

单细胞图谱

线虫衰老机制

Here we describe a single-cell atlas of aging for virtually every cell type of the nematode Caenorhabditis elegans. Our findings suggest that C. elegans aging is not random in nature, but rather chara

NIAID Data Ecosystem120

Effect of knocking down complex I subunit nuo-5 (ortholog of the human NDUFS1) in C.elegans. Effect of knocking down complex I subunit nuo-5 (ortholog of the human NDUFS1) in C.elegans

线虫衰老机制

转录组学分析

In this study we compared the transcriptomic profile in control L3 larvae with that of mild or strong (arrested) nuo-5 RNAi. The two treatment (mild and strong) in fact lead to two very different phen

NIAID Data Ecosystem30

Table2_The FGFR4 Homolog KIN-9 Regulates Lifespan and Stress Responses in Caenorhabditis elegans.XLSX

线虫衰老机制

应激反应通路

Fibroblast growth factor receptors (FGFRs) regulate diverse biological processes in eukaryotes. The nematode Caenorhabditis elegans is a good animal model for studying the roles of FGFR signaling and

NIAID Data Ecosystem30

Table_1_Simultaneous Ablation of the Catalytic AMPK α-Subunit SNF1 and Mitochondrial Matrix Protease CLPP Results in Pronounced Lifespan Extension.XLSX

寿命调控基因

线粒体能量代谢

Organismic aging is known to be controlled by genetic and environmental traits. Pathways involved in the control of cellular metabolism play a crucial role. Previously, we identified a role of PaCLPP,

NIAID Data Ecosystem50

Supplementary tables from Social divergence: molecular pathways underlying castes and longevity in a facultatively eusocial small carpenter bee

社会性昆虫分子机制

寿命调控基因

Unravelling the evolutionary origins of eusocial life is a longstanding endeavour in the field of evolutionary-developmental biology. Descended from solitary ancestors, eusocial insects such as honeyb

NIAID Data Ecosystem30

A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span

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