aPups (four litters) were genotyped on PND14. Chances of finding no surviving offspring having the Slc39a8(neo/neo)_BTZIP8-3(–) genotype, out of a total of 30 live births, gave a P-value of
The U2 snRNA is a basal component of the major spliceosome, which is responsible for >90% human pre-mRNA splicing. A 5-nucleotide deletion in one of the mouse U2 snRNA genes (Rnu2-8) causes cerebellar
Triple labeled confocal image of the dentate gyrus of a transgenic mouse engineered to overexpress alpha synuclein under the Thy-1 promotor, immunolabeled for mGluR5 (red), alpha synuclein (green) a