Crystal structure KPC-2 beta-lactamase complexed with WCK 5107 by co-crystallization
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Crystal structure KPC-2 beta-lactamase complexed with WCK 5107 by co-crystallization Descriptor: (2S,5R)-1-formyl-N'-[(3R)-piperidine-3-carbonyl]-5-[(sulfooxy)amino]piperidine-2-carbohydrazide, CHLORIDE ION, Carbapenem-hydrolyzing beta-lactamase KPC, ... Authors: van den Akker, F, Nguyen, N.Q. Deposit date: 2017-09-19 Release date: 2018-08-01 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.73 Å) Cite: Strategic Approaches to Overcome Resistance against Gram-Negative Pathogens Using beta-Lactamase Inhibitors and beta-Lactam Enhancers: Activity of Three Novel Diazabicyclooctanes WCK 5153, Zidebactam (WCK 5107), and WCK 4234. J. Med. Chem., 61, 2018
创建时间：
2017-09-19
