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Acyl-isothiocyanates as Efficient Thiocyanate Transfer Reagents

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NIAID Data Ecosystem2026-03-06 收录
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https://figshare.com/articles/dataset/Acyl_isothiocyanates_as_Efficient_Thiocyanate_Transfer_Reagents/2838499
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An unprecedented transfer of a thiocyanate (−SCN) group from aroyl/acyl isothiocyanate to alkyl or benzylic bromide is observed in the presence of a tertiary amine. This process is most effective when the bromomethyl proton is less acidic, while the presence of a more acidic proton gives 1,3-oxathiol-2-ylidine and other related products.
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2009-08-06
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