Organophotoredox-Catalyzed Vinyl Group Transfer Reaction: An Introduction to 4‑Vinyl-1,4-dihydropyridines

The
visible-light-driven, organophotoredox-catalyzed vinyl group
transfer reaction is described. The strategic use of proaromatic,
bench-stable, and readily prepared 4-vinyl-dihydropyridine (DHP) derivatives
triggers the vinyl group transfer that can couple stereoselectively
with fluorinated esters and amides to forge the C(sp3)–C(sp2) bond. The obtained products are transformed into diverse
fluorinated scaffolds. Preliminary mechanistic investigations are
outlined.