Several murine retinoblastoma models have been generated by deleting the genes encoding for retinoblastoma susceptibility protein pRb and one of its family members p107 or p130. In Rb-/-p107-/- retino

NIAID Data Ecosystem40

Genomic characterization of retinoblastoma (targeted sequencing)

癌症基因组数据

视网膜母细胞瘤

We studied primary retinoblastoma by targeted sequencing.EGA study EGAS00001005550

NIAID Data Ecosystem20

Supplementary Material for: Targeting HMGA2 in Retinoblastoma Cells in vitro Using the Aptamer Strategy

视网膜母细胞瘤

HMG-box蛋白

High-mobility group A2 (HMGA2) protein regulates retinoblastoma (RB) cancer cell proliferation. Here, a stable phosphorothioate-modified HMGA2 aptamer was used to block HMGA2 protein function in RB ce

DataCite Commons2020-09-04 更新60

Ubiquitin specific peptidase 33 promotes cell proliferation and reduces apoptosis through regulation of the SP1/PI3K/AKT pathway in retinoblastoma

视网膜母细胞瘤

PI3K/AKT信号通路

Ubiquitin-specific protease 33 (USP33), a deubiquitinating enzyme (DUB), has been identified to serve as a tumor suppressor or an oncogene in different cancers. However, its role in retinoblastoma (RB

DataCite Commons2024-02-16 更新40

Rb knockout retinal explant comparison

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