Dermorphin Blocks Apneic Response to Intravenous Bolus Injection of Fentanyl
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Rapid intravenous injection of overdose fentanyl triggers an immediate sustained apnea (ventilatory arrest), leading to sudden death within a few minutes in humans. Results in this study demonstrate that dermorphin pretreatment prevents the immediate apnea likely via desensitization of mu-opioid receptors in rats.
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figshare创建时间：
2025-10-31
