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Supplementary File S1 from PCSK5<sup>M452I</sup> Is a Recessive Hypomorph Exclusive to MCF10DCIS.com Cells

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NIAID Data Ecosystem2026-05-10 收录
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DEseq2 analysis of 3D spheroids prepared from MCF10DCIS.com cells reconstituted with wild-type (WT), hypomorphic (M452I), or null (T288P) PCSK5, and PCSK5T288P cultured with 250 ng/mL GDF11 for 8 days. Worksheets compare GDF11 relative to T288P, WT relative to T288P, and WT relative to M452I. Each sheet reports the log2 fold change, standard error (SE), DEseq2 statistics, and the mean and modeled counts for each condition from N = 4 biological replicates.

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2026-02-06
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