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PI3Kdelta in complex with the inhibitor GS-9901

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Protein Data Bank Japan2024-03-06 更新2026-03-21 收录
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PI3Kdelta in complex with the inhibitor GS-9901 Descriptor: 2,4-diamino-6-{[(S)-[5-chloro-8-fluoro-4-oxo-3-(pyridin-3-yl)-3,4-dihydroquinazolin-2-yl](cyclopropyl)methyl]amino}pyrimidine-5-carbonitrile, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Authors: Somoza, J.R, Villasenor, A. Deposit date: 2016-09-07 Release date: 2016-12-28 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.6 Å) Cite: The Discovery of GS-9901: A Potent, Selective and Metabolically Stable Inhibitor of PI3Kd To Be Published

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2016-09-07
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