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Human DNA Topoisomerase I (70 Kda) In Complex With The Indenoisoquinoline MJ-II-38 and Covalent Complex With A 22 Base Pair DNA Duplex

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Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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Human DNA Topoisomerase I (70 Kda) In Complex With The Indenoisoquinoline MJ-II-38 and Covalent Complex With A 22 Base Pair DNA Duplex Descriptor: 4-(5,11-DIOXO-5H-INDENO[1,2-C]ISOQUINOLIN-6(11H)-YL)BUTANOATE, 5'-D(*(TGP)P*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*T)-3', ... Authors: Staker, B.L, Feese, M.D, Cushman, M, Pommier, Y, Zembower, D, Stewart, L, Burgin, A.B. Deposit date: 2004-02-11 Release date: 2005-04-19 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (3 Å) Cite: Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex J.Med.Chem., 48, 2005
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2004-02-11
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