Cryo-EM structure of a human flippase mutant ATP11C Q79E-CDC50A in PtdCho-occluded E2-AlF state

Cryo-EM structure of a human flippase mutant ATP11C Q79E-CDC50A in PtdCho-occluded E2-AlF state Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Qian, Y, Abe, K. Deposit date: 2025-06-23 Release date: 2025-11-26 Last modified: 2025-12-17 Method: ELECTRON MICROSCOPY (2.39 Å) Cite: Cryo-EM structure of the ATP11C Q79E mutant reveals the structural basis for altered Phospholipid recognition. J.Biol.Chem., 302, 2025