HIV-CA Disulfide linked Hexamer bound to Quinazolin-4-one Scaffold inhibitor

HIV-CA Disulfide linked Hexamer bound to Quinazolin-4-one Scaffold inhibitor Descriptor: 2-[4-(4-aminobenzene-1-sulfonyl)-2-oxopiperazin-1-yl]-N-{(1R)-2-(3,5-difluorophenyl)-1-[3-(4-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl]ethyl}acetamide, Gag polyprotein Authors: Goldstone, D.C, Barnett, M.J, Taka, J.R.H. Deposit date: 2023-08-08 Release date: 2023-12-20 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Discovery, Crystallographic Studies, and Mechanistic Investigations of Novel Phenylalanine Derivatives Bearing a Quinazolin-4-one Scaffold as Potent HIV Capsid Modulators. J.Med.Chem., 66, 2023